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Scientists have discovered additional proof that an affordable diabetes drug may assist to sluggish aging and enhance overall well being. Metformin, the mostly-prescribed drug for sort 2 diabetes, has lengthy been co-opted as an unofficial anti-aging pill due to animal research that confirmed it extended lifespan and boosted metabolism. But it surely has down sides - similar to hindering stamina throughout exercise - and scientists hoping to improve it have faced a basic roadblock: it isn't clear exactly how metformin works, and how its advantages can be harnessed in a new drug without the down sides. Now, US researchers have offered a solution: metformin inflicts mild stress on the body, triggering sensors to restore metabolic steadiness that may swing off-kilter with age. The findings, printed right this moment within the journal Cell Reviews, give a lift to scientists who need to repurpose the $20 diabetes drug as a better anti-aging pill, and for those trying to improve the drug for the rising number of people with kind 2 diabetes.
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